NOD-IN-1

CAS No. 132819-92-2

NOD-IN-1( —— )

Catalog No. M11309 CAS No. 132819-92-2

A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 113 In Stock
10MG 186 In Stock
25MG 312 In Stock
50MG 464 In Stock
100MG 672 In Stock
500MG 1404 In Stock
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Biological Information

  • Product Name
    NOD-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
  • Description
    A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively; is 7-fold less potent than Noditinib-1 in terms of NOD1 inhibition and completely devoid of selective activity for NOD1 or NOD2 as opposed to Noditinib-1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD1|NOD2
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    132819-92-2
  • Formula Weight
    343.3969
  • Molecular Formula
    C18H17NO4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(C(N1S(=O)(C2=CC=C(C)C=C2)=O)=CC3=C1C=CC=C3)OCC
  • Chemical Name
    1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ke?ek Ple?ec K, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.
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