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NBC19
CAS No. 2068818-75-5
NBC19( NBC 19 )
Catalog No. M13217 CAS No. 2068818-75-5
NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 977 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNBC19
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NoteResearch use only, not for human use.
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Brief DescriptionNBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
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DescriptionNBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
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In Vitro——
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In Vivo——
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SynonymsNBC 19
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PathwayNF-κB
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TargetNOD
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RecptorNOD
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Research Area——
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Indication——
Chemical Information
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CAS Number2068818-75-5
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Formula Weight491.644
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Molecular FormulaC24H26BCl3N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name1-(6-(cyclohexylamino)-2,2-diphenyl-4-(trichloromethyl)-2,3-dihydro-1l3,3,2l4-oxazaborinin-5-yl)ethan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Redondo-Castro E, et al. Sci Rep. 2018 Apr 4;8(1):5667.
2. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5.
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