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N3-PEG3-CH2COOH

CAS No. 172531-37-2

N3-PEG3-CH2COOH( Azido-PEG3-CH2CO2H )

Catalog No. M12622 CAS No. 172531-37-2

A PEG3 linker for PROTAC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N3-PEG3-CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    A PEG3 linker for PROTAC.
  • Description
    A PEG3 linker for PROTAC.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Azido-PEG3-CH2CO2H
  • Pathway
    PROTACs
  • Target
    PEGn
  • Recptor
    PEGn
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    172531-37-2
  • Formula Weight
    233.224
  • Molecular Formula
    C8H15N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(COCCOCCOCCN=[N+]=[N-])=O
  • Chemical Name
    2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.
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