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N-Formyl-Met-Leu-Phe-Lys

CAS No. 67247-11-4

N-Formyl-Met-Leu-Phe-Lys ( fMLFK )

Catalog No. M22300 CAS No. 67247-11-4

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Formyl-Met-Leu-Phe-Lys
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.
  • Description
    N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.
  • Synonyms
    fMLFK
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    FPR1;FPR2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    67247-11-4
  • Formula Weight
    565.73
  • Molecular Formula
    C27H43N5O6S
  • Purity
    >98% (HPLC)
  • Solubility
    H2O
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306.
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