N-Acetyl-Calicheamicin
CAS No. 108212-76-6
N-Acetyl-Calicheamicin ( N-Acetyl-Calicheamicin γ;N-Acetyl-γ-calicheamicin )
Catalog No. M10325 CAS No. 108212-76-6
N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 1017 | Get Quote |
|
10MG | 1368 | Get Quote |
|
25MG | 2025 | Get Quote |
|
50MG | 2673 | Get Quote |
|
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameN-Acetyl-Calicheamicin
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.
-
DescriptionN-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission; a ADC payload in antibody drug conjugates development.
-
SynonymsN-Acetyl-Calicheamicin γ;N-Acetyl-γ-calicheamicin
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorAntibacterial
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number108212-76-6
-
Formula Weight1410.39
-
Molecular FormulaC57H76IN3O22S4
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCCN(C1COC(CC1OC)OC2C(C(C(OC2OC3C#CC=CC#CC4(CC(=O)C(=C3C4=CCSSSC)NC(=O)OC)O)C)NOC5CC(C(C(O5)C)SC(=O)C6=C(C(=C(C(=C6OC)OC)OC7C(C(C(C(O7)C)O)OC)O)I)C)O)O)C(=O)C
-
Chemical NameCarbamic acid, [(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyrano
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Stasi R, et al. Cancer Treat Rev. 2008 Feb;34(1):49-60.
2. Naito K, et al. Leukemia. 2000 Aug;14(8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96.
2. Naito K, et al. Leukemia. 2000 Aug;14(8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96.
molnova catalog
related products
-
2,6-Dichlorodiphenyl...
2,6-Dichlorodiphenylamine shows activity against Candida albicans infections. 2,6-Dichlorodiphenylamine elevated the MIC by 4-fold of diclofenac sodium (DFNa).
-
WAY-658650
WAY-658650 has antibacterial activity against Mycobacterium tuberculosis.
-
ANT431
ANT431 is a novel potent metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2.