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Monascin
CAS No. 21516-68-7
Monascin( —— )
Catalog No. M21781 CAS No. 21516-68-7
Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMonascin
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NoteResearch use only, not for human use.
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Brief DescriptionMonascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice).
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DescriptionMonascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor).
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In Vitro——
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In VivoMonascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin. Animal Model:SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter. Dosage:0.0025% in drinking water.Administration:Orally daily for 2 weeks in drinking water.Result:Reduced the number of the papillomas.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number21516-68-7
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Formula Weight358.43
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Molecular FormulaC??H??O?
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (139.50 mM)
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SMILESO=C([C@@H]1C(CCCCC)=O)O[C@]2(C)[C@]1([H])CC(C=C(/C=C/C)OC3)=C3C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Akihisa T, et al. Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice). Chem Biodivers. 2005 Oct;2(10):1305-9.
2. Lee CL, et al. Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent--monacolin K and antiinflammation agent--monascin. Appl Microbiol Biotechnol. 2006 Oct;72(6):1254-62.
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