
Mofarotene
CAS No. 125533-88-2
Mofarotene( —— )
Catalog No. M36197 CAS No. 125533-88-2
Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tumors and respiratory diseases.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 166 | Get Quote |
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5MG | 257 | Get Quote |
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10MG | 380 | Get Quote |
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25MG | 615 | Get Quote |
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50MG | 873 | Get Quote |
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100MG | 1161 | Get Quote |
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500MG | 2322 | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameMofarotene
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NoteResearch use only, not for human use.
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Brief DescriptionMofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tumors and respiratory diseases.
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DescriptionMofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tumors and respiratory diseases.Mofarotene is a retinoic acid analog that binds to and activates retinoic acid receptors (RARs), which alters the expression of certain genes, leading to reduced cell differentiation and cell proliferation in susceptible cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetRetinoid Receptor
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RecptorRetinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number125533-88-2
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Formula Weight433.63
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Molecular FormulaC29H39NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1(C)C=2C(C(C)(C)CC1)=CC=C(\C(=C\C3=CC=C(OCCN4CCOCC4)C=C3)\C)C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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CD 1530
CD 1530 is a selective and potent RARγ agonist (Kd:150 nM) with potential anticancer activity, shows insecticidal activity against Cryptobacterium hidradii nematodes, and can be used to study oral carcinogenesis.
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LG-100064
LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)LG-100064 shows no effect on RARα/β/γ (EC50, >10000 nM).LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ.
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Halofuginone
Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.