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Midodrine

CAS No. 42794-76-3

Midodrine( ±)-Midodrine )

Catalog No. M14451 CAS No. 42794-76-3

Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Midodrine
  • Note
    Research use only, not for human use.
  • Brief Description
    Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
  • Description
    Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension; activates the alpha-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure; does not stimulate cardiac beta-adrenergic receptors, and diffuses poorly across the blood-brain barrier.Hypertension Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ±)-Midodrine
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Hypertension

Chemical Information

  • CAS Number
    42794-76-3
  • Formula Weight
    254.2823
  • Molecular Formula
    C12H18N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN
  • Chemical Name
    Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. McTavish D, et al. Drugs. 1989 Nov;38(5):757-77. 2. Pittner H, et al. Arzneimittelforschung. 1976;26(12):2145-54. 3. Kontani H, et al. Jpn J Pharmacol. 1992 Apr;58(4):339-46. 4. Brune ME, et al. J Urol. 2001 Oct;166(4):1555-9.
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