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Midazolam
CAS No. 59467-70-8
Midazolam( Dormicum | Versed )
Catalog No. M15206 CAS No. 59467-70-8
Midazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMidazolam
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NoteResearch use only, not for human use.
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Brief DescriptionMidazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties.
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DescriptionMidazolam (Dormicum;Versed) is a short-acting benzodiazepine derivative with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties; exerts its effect by binding to the benzodiazepine receptor at GABA receptor-chloride ionophore complex in the central nervous system (CNS), leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS.Epilepsy Approved.
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In Vitro——
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In Vivo——
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SynonymsDormicum | Versed
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGAT
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Research AreaNeurological Disease
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IndicationEpilepsy
Chemical Information
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CAS Number59467-70-8
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Formula Weight325.78
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Molecular FormulaC18H13ClFN3
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
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Chemical Name8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gerecke M.Br J Clin Pharmacol. 1983;16 Suppl 1:11S-16S.
2. Polc P, et al. Brain Res. 1981 Jul 27;217(1):216-20.
3. Stryker TD, et al. Brain Res. 1986 Jan 8;362(2):339-43.
4. Audi EA, et al. Eur J Pharmacol. 1984 Aug 17;103(3-4):279-85.
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