MethADP

CAS No. 3768-14-7

MethADP( —— )

Catalog No. M33017 CAS No. 3768-14-7

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) is a specific CD73 inhibitor that inhibits the enzyme ecto-5′-nucleotidase (ecto), which has been used in the study of neurological and cardiovascular diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 301 Get Quote
5MG 471 Get Quote
10MG 658 Get Quote
25MG 984 Get Quote
50MG 1334 Get Quote
100MG 1764 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MethADP
  • Note
    Research use only, not for human use.
  • Brief Description
    MethADP (Adenosine 5'-(α,β-methylene)diphosphate) is a specific CD73 inhibitor that inhibits the enzyme ecto-5′-nucleotidase (ecto), which has been used in the study of neurological and cardiovascular diseases.
  • Description
    MethADP is a specific CD73 inhibitor.
  • In Vitro
    MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CD73
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3768-14-7
  • Formula Weight
    425.23
  • Molecular Formula
    C11H17N5O9P2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(CP(=O)(O)O)(=O)O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202.?
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