Metergoline

CAS No. 17692-51-2

Metergoline( Metergoline )

Catalog No. M18131 CAS No. 17692-51-2

Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder therapy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Metergoline
  • Note
    Research use only, not for human use.
  • Brief Description
    Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder therapy.
  • Description
    Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for MIGRAINE DISORDERS therapy.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male albino mice (25-40 g)Dosage:5 mg/kg Administration:Intraperitoneal injection Result:Inhibited bites or scratches induced by 5-HT (2 μg).
  • Synonyms
    Metergoline
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    5-HT1| 5-HT2| 5-HT2| 5-HT2| 5-HT7
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    17692-51-2
  • Formula Weight
    403.52
  • Molecular Formula
    C25H29N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL 123.91 mM;H2O : < 0.1 mg/mL
  • SMILES
    CN1C[C@@H](C[C@H]2[C@H]1Cc1cn(c3cccc2c13)C)CNC(=O)OCc1ccccc1
  • Chemical Name
    Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Millan, M.J.,Newman-Tancredi, A.,Lochon, S., et al. Biochem. Behav. 71(4), 589-598 (2002).
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