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Mesna

CAS No. 19767-45-4

Mesna ( Coenzyme M; HS-CoM; 2-Mercaptoethanesulfonate; UCB 3983 )

Catalog No. M13089 CAS No. 19767-45-4

Mesna(Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mesna
  • Note
    Research use only, not for human use.
  • Brief Description
    Mesna(Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.
  • Description
    Mesna(Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.
  • Synonyms
    Coenzyme M; HS-CoM; 2-Mercaptoethanesulfonate; UCB 3983
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    19767-45-4
  • Formula Weight
    164.18
  • Molecular Formula
    C2H5NaO3S2
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 7 mg/mL (42.63 mM); DMSO: 33 mg/mL (200.99 mM)
  • SMILES
    SCCS(=O)([O-])=O.[Na+]
  • Chemical Name
    sodium 2-mercaptoethanesulfonate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kalcioglu MT, et al. Am J Otolaryngol. 2014 May-Jun;35(3):357-6
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