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Mequitazine

CAS No. 29216-28-2

Mequitazine ( Mequitazine; Primalan; Mircol; Metaplexan )

Catalog No. M18376 CAS No. 29216-28-2

Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 38 In Stock
10MG 52 In Stock
25MG 82 In Stock
50MG 112 In Stock
100MG 140 In Stock
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Biological Information

  • Product Name
    Mequitazine
  • Note
    Research use only, not for human use.
  • Brief Description
    Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.
  • Description
    Mequitazine is a potent histamine H1 antagonist or antihistamine. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. Mequitazine provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
  • Synonyms
    Mequitazine; Primalan; Mircol; Metaplexan
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    H1 receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    29216-28-2
  • Formula Weight
    322.47
  • Molecular Formula
    C20H22N2S
  • Purity
    98%
  • Solubility
    DMSO : 16 mg/mL 49.62 mM;
  • SMILES
    C(C1CN2CCC1CC2)N1c2ccccc2Sc2ccccc12
  • Chemical Name
    10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gonnot V, et al. Expedient synthesis of mequitazine an antihistaminic drug by palladium catalyzed allylic alkylation of sodium phenothiazinate. Chem Pharm Bull (Tokyo). 2009 Nov;57(11):1300-2.
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