Mequitazine ( Mequitazine; Primalan; Mircol; Metaplexan )

Catalog No. M18376 CAS No. 29216-28-2

Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.

Purity : 98%

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5MG	38	In Stock
10MG	52	In Stock
25MG	82	In Stock
50MG	112	In Stock
100MG	140	In Stock
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Biological Information

Product Name

Mequitazine
Note

Research use only, not for human use.
Brief Description

Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.
Description

Mequitazine is a potent histamine H1 antagonist or antihistamine. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. Mequitazine provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Synonyms

Mequitazine; Primalan; Mircol; Metaplexan
Pathway

Others
Target

Other Targets
Recptor

H1 receptor
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

29216-28-2
Formula Weight

322.47
Molecular Formula

C20H22N2S
Purity

98%
Solubility

DMSO : 16 mg/mL 49.62 mM;
SMILES

C(C1CN2CCC1CC2)N1c2ccccc2Sc2ccccc12
Chemical Name

10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gonnot V, et al. Expedient synthesis of mequitazine an antihistaminic drug by palladium catalyzed allylic alkylation of sodium phenothiazinate. Chem Pharm Bull (Tokyo). 2009 Nov;57(11):1300-2.

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