Meglumine

CAS No. 6284-40-8

Meglumine( 1-Deoxy-1-(methylamino)-D-glucitol | Iosulamide | N-Methyl-D-glucamine )

Catalog No. M15376 CAS No. 6284-40-8

Meglumine is an amino sugar derived from sorbitol.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 45 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Meglumine
  • Note
    Research use only, not for human use.
  • Brief Description
    Meglumine is an amino sugar derived from sorbitol.
  • Description
    Meglumine is an amino sugar derived from sorbitol. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine and iodipamide meglumine.
  • In Vitro
    Western Blot Analysis Cell Line:C2C12 mouse myoblasts Concentration:0, 10, 30, 100, 300 mM or 200 mM Incubation Time:60 min or 0, 10, 30, 60, 120 min Result:Increased the levels of SNARK protein in a dose-dependent manner after 60 min and reached a plateau at 30 minutes.
  • In Vivo
    Animal Model:Sprague-Dawley ratDosage:25 or 50 mM Administration:p.o., dissolve in water Result:Reduced the isoprostane levels in rats.Animal Model:K6/ODC transgenic mice Dosage:37.5 mM Administration:p.o., dissolve in water Result:Reduced the number of skin tumors and inhibited tumor growth.Animal Model:KK.Cg-Ay/J mice Dosage:18 mM Administration:p.o., in drinking water Result:Performed better in a glucose tolerance test.Decreased their average fasting levels of glucose and triglyceride levels in both the liver and blood serum.
  • Synonyms
    1-Deoxy-1-(methylamino)-D-glucitol | Iosulamide | N-Methyl-D-glucamine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    6284-40-8
  • Formula Weight
    195.21
  • Molecular Formula
    C7H17NO5
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 39 mg/mL (199.78 mM); DMSO: 39 mg/mL (199.78 mM)
  • SMILES
    O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC
  • Chemical Name
    (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Navaei A, et al. Drug Dev Ind Pharm. 2014 Jun;40(6):701-10.
molnova catalog
related products
  • epi-Progoitrin

    Epiprogoitrin is a epimer that can be deglycosylated to epigoitrin.

  • Alopecurone A

    Alopecurone A exhibits potent inhibitory activity on MRP1.

  • PUMA BH3

    PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.