Mc-Val-Cit-PAB-Cl

CAS No. 1639351-92-0

Mc-Val-Cit-PAB-Cl ( —— )

Catalog No. M26985 CAS No. 1639351-92-0

Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 338 Get Quote
10MG 502 Get Quote
25MG 808 Get Quote
50MG 1107 Get Quote
100MG 1494 Get Quote
500MG 2988 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Mc-Val-Cit-PAB-Cl
  • Note
    Research use only, not for human use.
  • Brief Description
    Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
  • Description
    Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Mc-Val-Cit-PAB-Cl is a cleavable ADC linker.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1639351-92-0
  • Formula Weight
    591.1
  • Molecular Formula
    C28H39ClN6O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CCl)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Remirez D, et al. Mechanism of protection of lobenzarit against paracetamol-induced toxicity in rat hepatocytes. Eur J Pharmacol. 1995 Dec 7;293(4):301-8.
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