Mc-Val-Cit-PAB-Cl( —— )

Catalog No. M26985 CAS No. 1639351-92-0

Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	338	Get Quote
10MG	502	Get Quote
25MG	808	Get Quote
50MG	1107	Get Quote
100MG	1494	Get Quote
500MG	2988	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Mc-Val-Cit-PAB-Cl
Note

Research use only, not for human use.
Brief Description

Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
Description

Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Mc-Val-Cit-PAB-Cl is a cleavable ADC linker.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

1639351-92-0
Formula Weight

591.11
Molecular Formula

C28H39ClN6O6
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CCl)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Remirez D, et al. Mechanism of protection of lobenzarit against paracetamol-induced toxicity in rat hepatocytes. Eur J Pharmacol. 1995 Dec 7;293(4):301-8.

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