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MX107

CAS No. 2170102-50-6

MX107( MX 107 )

Catalog No. M13464 CAS No. 2170102-50-6

MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MX107
  • Note
    Research use only, not for human use.
  • Brief Description
    MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM.
  • Description
    MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM; significantly enhances the tumoricidal efficacy of doxorubicin in TNBC cells, induces degradation of XIAP and/or cIAP1, which inhibited NF-κB activation by genotoxic agents.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MX 107
  • Pathway
    Apoptosis
  • Target
    IAP
  • Recptor
    IAP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2170102-50-6
  • Formula Weight
    376.5
  • Molecular Formula
    C24H28N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC1=C2N=CC=CC2=C(COCC3=CC=C(CC)C=C3)C=C1CN4CCCC4
  • Chemical Name
    5-(((4-ethylbenzyl)oxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang W, et al. J Pharmacol Exp Ther. 2018 May 7. pii: jpet.118.249151.
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