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MX106
CAS No. 2170836-81-2
MX106( MX 106 )
Catalog No. M13467 CAS No. 2170836-81-2
MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
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| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMX106
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NoteResearch use only, not for human use.
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Brief DescriptionMX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.
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DescriptionMX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM; significantly enhances the tumoricidal efficacy of doxorubicin in TNBC cells, induces degradation of XIAP and/or cIAP1, which inhibited NF-κB activation by genotoxic agents.
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In Vitro——
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In Vivo——
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SynonymsMX 106
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PathwayApoptosis
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TargetIAP
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RecptorIAP
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Research Area——
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Indication——
Chemical Information
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CAS Number2170836-81-2
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Formula Weight390.527
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Molecular FormulaC25H30N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESOC1=C2N=CC=CC2=C(COCC3=CC=C(C(C)C)C=C3)C=C1CN4CCCC4
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Chemical Name5-(((4-isopropylbenzyl)oxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang W, et al. J Pharmacol Exp Ther. 2018 May 7. pii: jpet.118.249151.
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