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MTIC

CAS No. 3413-72-7

MTIC( —— )

Catalog No. M34781 CAS No. 3413-72-7

MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    MTIC
  • Note
    Research use only, not for human use.
  • Brief Description
    MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity.
  • Description
    MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Drug Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3413-72-7
  • Formula Weight
    168.16
  • Molecular Formula
    C5H8N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (148.67 mM; Ultrasonic (<60°C)
  • SMILES
    CN\N=N\c1[nH]cnc1C(N)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ramalho MJ, et al. Biophysical interaction of temozolomide and its active metabolite with biomembrane models: The relevance of drug-membrane interaction for Glioblastoma Multiforme therapy. Eur J Pharm Biopharm. 2019;136:156-163. ?
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