MT-DADMe-ImmA
CAS No. 653592-04-2
MT-DADMe-ImmA ( Methylthio-DADMe-Immucillin A; MTDIA )
Catalog No. M29593 CAS No. 653592-04-2
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 123 | Get Quote |
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10MG | 213 | Get Quote |
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25MG | 402 | Get Quote |
|
50MG | 593 | Get Quote |
|
100MG | 845 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameMT-DADMe-ImmA
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NoteResearch use only, not for human use.
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Brief DescriptionMT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).
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DescriptionMT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).(In Vitro):Treatment of cultured cells with MTA and MT-DADMe-ImmA inhibit MTAP, increase cellular MTA concentrations, decrease polyamines, and induce apoptosis in FaDu and Cal27, two head and neck squamous cell carcinoma cell lines. MT-DADMe-ImmA alone does not induce apoptosis in any cell line .(In Vivo):MTAP activity slowly returns, giving a biological half-life for the action of oral MT-DADMe-ImmA of 6.3 days. The time-dependent growth of FaDu tumors in immunodeficient mice is suppressed by oral or intraperitoneal treatment with MT-DADMe-ImmA .
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SynonymsMethylthio-DADMe-Immucillin A; MTDIA
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number653592-04-2
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Formula Weight293.4
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Molecular FormulaC13H19N5OS
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Purity>98% (HPLC)
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Solubility——
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SMILESCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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