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MSC2504877
CAS No. 1460286-21-8
MSC2504877 ( 3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one )
Catalog No. M28544 CAS No. 1460286-21-8
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 138 | Get Quote |
|
| 10MG | 219 | Get Quote |
|
| 25MG | 426 | Get Quote |
|
| 50MG | 624 | Get Quote |
|
| 100MG | 889 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMSC2504877
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NoteResearch use only, not for human use.
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Brief DescriptionMSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
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DescriptionMSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
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Synonyms3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
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PathwayOthers
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TargetOther Targets
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RecptorPTP1B
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Research Area——
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Indication——
Chemical Information
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CAS Number1460286-21-8
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Formula Weight282.3
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Molecular FormulaC17H18N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NC(=CN2C1=CC=C2C)C=3C=CC(=CC3)C(O)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Steinhauer J, et al. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec;20(24):5224-35.
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