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MSC2360844
CAS No. 1305267-37-1
MSC2360844 ( —— )
Catalog No. M26310 CAS No. 1305267-37-1
MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | Get Quote |
|
| 10MG | 286 | Get Quote |
|
| 25MG | 560 | Get Quote |
|
| 50MG | 897 | Get Quote |
|
| 100MG | 1422 | Get Quote |
|
| 500MG | 2844 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMSC2360844
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NoteResearch use only, not for human use.
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Brief DescriptionMSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).
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DescriptionMSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).(In Vitro):MSC2360844 inhibits B cell proliferation in a concentration-dependent manner with an IC50 of 48?nM. MSC2360844 blocks BCR- and TCR-mediated responses in lymphocytes and TLR-induced IFNα by pDC in human primary cells.(In Vivo):in a murine SLE model，MSC2360844 ameliorates disease manifestations .
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number1305267-37-1
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Formula Weight526.6
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Molecular FormulaC26H27FN4O5S
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Purity>98% (HPLC)
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Solubility——
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SMILESFc1cccc2-c3c(CS(=O)(=O)c12)c(nn3-c1ccc(CN2CCOCC2)cc1)C(=O)N1CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Magedov IV, et, al. Reengineered epipodophyllotoxin. Chem Commun (Camb). 2012 Oct 28; 48(84): 10416-8.
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