Cart
sales@molnova.com
Home - Products - Others - Other Targets - MRT-81

MRT-81

CAS No. 1263132-08-6

MRT-81 ( —— )

Catalog No. M28744 CAS No. 1263132-08-6

MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 114 Get Quote
5MG 192 Get Quote
10MG 309 Get Quote
25MG 525 Get Quote
50MG 750 Get Quote
100MG 1035 Get Quote
500MG 2061 Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MRT-81
  • Note
    Research use only, not for human use.
  • Brief Description
    MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer.
  • Description
    MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer.(In Vitro):MRT-81 inhibits the differentiation of the mesenchymal pluripotent C3H10T1/2 cells into alkaline phosphatase positive osteoblasts induced by the Smo agonist SAG with 0.1 μM, with an IC50?value of 64 nM.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    hDHODH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1263132-08-6
  • Formula Weight
    555.7
  • Molecular Formula
    C31H29N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1ccc(C)c(NC(=O)c2ccc(cc2)-c2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Munier-Lehmann H, et al. Original?2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine?derivatives?as?inhibitors?of?human?dihydroorotate?dehydrogenase?(DHODH). J Med Chem.?2015 Jan 22;58(2):860-77.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Retrofractamide C

    The fruits of Piper nigrum L.

  • 3-TYP

    3-TYP is a selectiveSIRT3inhibitor.

  • TS-011

    TS-011 is a selective 20-Hydroxyeicosatetraenoic acid synthesis inhibitor.

Sign In Join Free