Cart
sales@molnova.com
MMP2-IN-2
CAS No. 1772-39-0
MMP2-IN-2( —— )
Catalog No. M35438 CAS No. 1772-39-0
MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | In Stock |
|
| 5MG | 73 | In Stock |
|
| 10MG | 117 | In Stock |
|
| 25MG | 220 | In Stock |
|
| 50MG | 348 | In Stock |
|
| 100MG | 557 | In Stock |
|
| 500MG | 1152 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMMP2-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionMMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
-
DescriptionMMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetMMP
-
RecptorMMP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1772-39-0
-
Formula Weight284.23
-
Molecular FormulaC13H8N4O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 7.14 mg/mL (25.12 mM; Ultrasonic (<60°C)
-
SMILESO=[N+]([O-])C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257. ?
molnova catalog
related products
-
CTTHWGFTLC, CYCLIC
This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
-
NNGH
NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane binding.
-
AGPS-IN-2i
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.
