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MMP-12 Inhibitor

CAS No. 1258003-93-8

MMP-12 Inhibitor( MMP408 | MMP12 )

Catalog No. M28533 CAS No. 1258003-93-8

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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25MG	1096	In Stock
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Biological Information

Product Name

MMP-12 Inhibitor
Note

Research use only, not for human use.
Brief Description

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
Description

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.(In Vitro):MMP-12 Inhibitor shows weaker activity against human MMP-3, MMP-13, and MMP-14 with IC50s of 351, 120, and 1100 nM.(In Vivo):In mice, MMP-12 Inhibitor (5 mg/kg, p.o.) effectively alleviates rhMMP-12-induced pulmonary inflammatory response by more than 50%.
In Vitro

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In Vivo

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Synonyms

MMP408 | MMP12
Pathway

Metabolic Enzyme/Protease
Target

MMP
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

1258003-93-8
Formula Weight

420.44
Molecular Formula

C19H20N2O7S
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C(OC)=O)C=1C=C2C=3C(OC2=CC1)=CC(S(N[C@H](C(C)C)C(O)=O)(=O)=O)=CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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