MMAD

CAS No. 203849-91-6

MMAD ( MMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10 )

Catalog No. M18216 CAS No. 203849-91-6

MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 59 In Stock
10MG 104 In Stock
50MG 337 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MMAD
  • Note
    Research use only, not for human use.
  • Brief Description
    MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).
  • Description
    MMAD, also known as Monomethyl auristatin D, is a highly potent tubulin inhibitor. MMAD is one of the auristatins, which are used as antibody drug conjugates (ADCs).
  • Synonyms
    MMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    Microtubule/Tubulin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    203849-91-6
  • Formula Weight
    771.06
  • Molecular Formula
    C41H66N6O6S
  • Purity
    98%
  • Solubility
    DMSO : 24.5 mg/mL 31.77 mM;
  • SMILES
    O=C(N[C@@H](Cc1ccccc1)c2nccs2)[C@H](C)[C@@H](OC)[C@@H]3CCCN3C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
  • Chemical Name
    (S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
molnova catalog
related products
  • Desvenlafaxine

    Desvenlafaxine (O-desmethylvenlafaxine) the major active metabolite of venlafaxine, is an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class).

  • Cyproheptadine hydro...

    Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2.

  • Citalopram HBr

    Citalopram hydrobromide belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).