MMAD
CAS No. 203849-91-6
MMAD ( MMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10 )
Catalog No. M18216 CAS No. 203849-91-6
MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 59 | In Stock |
|
10MG | 104 | In Stock |
|
50MG | 337 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMMAD
-
NoteResearch use only, not for human use.
-
Brief DescriptionMMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).
-
DescriptionMMAD, also known as Monomethyl auristatin D, is a highly potent tubulin inhibitor. MMAD is one of the auristatins, which are used as antibody drug conjugates (ADCs).
-
SynonymsMMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
RecptorMicrotubule/Tubulin
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number203849-91-6
-
Formula Weight771.06
-
Molecular FormulaC41H66N6O6S
-
Purity98%
-
SolubilityDMSO : 24.5 mg/mL 31.77 mM;
-
SMILESO=C(N[C@@H](Cc1ccccc1)c2nccs2)[C@H](C)[C@@H](OC)[C@@H]3CCCN3C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
-
Chemical Name(S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
molnova catalog
related products
-
Desvenlafaxine
Desvenlafaxine (O-desmethylvenlafaxine) the major active metabolite of venlafaxine, is an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class).
-
Cyproheptadine hydro...
Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2.
-
Citalopram HBr
Citalopram hydrobromide belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).