MMAD
CAS No. 203849-91-6
MMAD ( MMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10 )
Catalog No. M18216 CAS No. 203849-91-6
MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 59 | In Stock |
|
10MG | 104 | In Stock |
|
50MG | 337 | In Stock |
|
100MG | Get Quote | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameMMAD
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NoteResearch use only, not for human use.
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Brief DescriptionMMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs).
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DescriptionMMAD, also known as Monomethyl auristatin D, is a highly potent tubulin inhibitor. MMAD is one of the auristatins, which are used as antibody drug conjugates (ADCs).
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SynonymsMMAD, Demethyldolastatin 10; Monomethyl Dolastatin 10
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorMicrotubule/Tubulin
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number203849-91-6
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Formula Weight771.06
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Molecular FormulaC41H66N6O6S
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Purity98%
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SolubilityDMSO : 24.5 mg/mL 31.77 mM;
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SMILESO=C(N[C@@H](Cc1ccccc1)c2nccs2)[C@H](C)[C@@H](OC)[C@@H]3CCCN3C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
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Chemical Name(S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
molnova catalog
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