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ML418
CAS No. 1928763-08-9
ML418 ( —— )
Catalog No. M22132 CAS No. 1928763-08-9
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 113 | In Stock |
|
| 10MG | 178 | In Stock |
|
| 25MG | 313 | In Stock |
|
| 50MG | 478 | In Stock |
|
| 100MG | 691 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML418
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NoteResearch use only, not for human use.
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Brief DescriptionML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
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DescriptionML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorKir7.1
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Research Area——
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Indication——
Chemical Information
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CAS Number1928763-08-9
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Formula Weight377.87
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Molecular FormulaC19H24ClN3O3
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Purity>98% (HPLC)
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SolubilityDMSO:20 mg/mL?(52.93 mM;?Need ultrasonic)
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SMILESCC(C)OC(=O)NC1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.
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