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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - ML418

ML418

CAS No. 1928763-08-9

ML418 ( —— )

Catalog No. M22132 CAS No. 1928763-08-9

ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 178 In Stock
25MG 313 In Stock
50MG 478 In Stock
100MG 691 In Stock
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Biological Information

  • Product Name
    ML418
  • Note
    Research use only, not for human use.
  • Brief Description
    ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
  • Description
    ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Kir7.1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1928763-08-9
  • Formula Weight
    377.87
  • Molecular Formula
    C19H24ClN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:20 mg/mL?(52.93 mM;?Need ultrasonic)
  • SMILES
    CC(C)OC(=O)NC1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.
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