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ML367

CAS No. 381168-77-0

ML367( —— )

Catalog No. M20178 CAS No. 381168-77-0

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML367
  • Note
    Research use only, not for human use.
  • Brief Description
    ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
  • Description
    ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
  • In Vitro
    Western Blot Analysis Cell Line:HEK293T cells Concentration:0-40 μM in the presence or absence of 20 μM 5-Furd Incubation Time:16 hours Result:Inhibited the increased ATAD5 protein levels induced by 5-Furd.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATAD5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    381168-77-0
  • Formula Weight
    334.32
  • Molecular Formula
    C19H12F2N4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120 mg/mL?(358.94 mM)
  • SMILES
    Fc1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1F
  • Chemical Name
    (S)-9b-(4-Chlorophenyl)-1-(34-difluorobenzoyl)-23-dihydro-1H-imidazo[21-a]isoindol-5(9bH)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rohde JM et al. Discovery of ML367 inhibitor of ATAD5 stabilization. Probe Reports from the NIH Molecular Libraries Program.
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