Cart
sales@molnova.com
ML327
CAS No. 1883510-31-3
ML327( ML 327 )
Catalog No. M12930 CAS No. 1883510-31-3
ML327 is a small molecule that restores E-cadherin expression through regulation of E-cadherin transcription.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 102 | In Stock |
|
| 10MG | 160 | In Stock |
|
| 25MG | 335 | In Stock |
|
| 50MG | 537 | In Stock |
|
| 100MG | 767 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML327
-
NoteResearch use only, not for human use.
-
Brief DescriptionML327 is a small molecule that restores E-cadherin expression through regulation of E-cadherin transcription.
-
DescriptionML327 is a small molecule that restores E-cadherin expression through regulation of E-cadherin transcription, displays an In-Cell Western EC50 of 1.0 uM; is inactive (>30 uM) against all know epigenetic targets (HDACs, MMPs, Sirtuins, etc.) that increase E-cadherin expression, and clean in a Ricerca ancillary pharmacology panel; possesses favorable physiochemical properties, an excellent dystrophia myotonica protein kinase (DMPK) profile.
-
In Vitro——
-
In Vivo——
-
SynonymsML 327
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetCadherin
-
RecptorMYC
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1883510-31-3
-
Formula Weight366.377
-
Molecular FormulaC19H18N4O4
-
Purity>98% (HPLC)
-
SolubilityDMSO: 32 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESC1C=CNC(=O)C=1C(=O)NCCCNC(=O)C1=NOC(C2=CC=CC=C2)=C1
-
Chemical NameN-(3-(2-Hydroxynicotinamido)propyl)-5-phenylisoxazole-3-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. An H, et al. Oncotarget. 2015 Sep 8;6(26):22934-48.
2. Brogan JT, et al. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4260-4.
3. Rellinger EJ, et al. Oncotarget. 2017 Jul 20;8(53):91040-91051.
4. Rellinger EJ, et al. Biochem Biophys Res Commun. 2017 Sep 16;491(2):463-468.
molnova catalog
related products
