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ML297

CAS No. 1443246-62-5

ML297 ( ML297; ML 297; ML-297 )

Catalog No. M18019 CAS No. 1443246-62-5

ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).

Purity : 97%

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	65	In Stock
10MG	110	In Stock
25MG	205	In Stock
50MG	308	In Stock
100MG	478	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ML297
Note

Research use only, not for human use.
Brief Description

ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).
Description

ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
Synonyms

ML297; ML 297; ML-297
Pathway

Others
Target

Other Targets
Recptor

GIRK1/2
Research Area

——
Indication

——

Chemical Information

CAS Number

1443246-62-5
Formula Weight

328.11
Molecular Formula

C17H14F2N4O
Purity

97%
Solubility

——
SMILES

Fc1ccc(cc1F)NC(=O)Nc3cc(C)nn3c2ccccc2
Chemical Name

1-(3,4-difluorophenyl)-3-(5-methyl-2-phenylpyrazol-3-yl)urea

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Neuropsychopharmacology. 2017 Aug;42(9):1800-1812.

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