ML265
CAS No. 1221186-53-3
ML265 ( TEPP-46 )
Catalog No. M20635 CAS No. 1221186-53-3
ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 87 | In Stock |
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10MG | 132 | In Stock |
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50MG | 336 | In Stock |
|
100MG | Get Quote | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameML265
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NoteResearch use only not for human use.
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Brief DescriptionML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?.
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DescriptionML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?
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SynonymsTEPP-46
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PathwayOthers
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TargetOther Targets
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RecptorPKM2
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Research Area——
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Indication——
Chemical Information
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CAS Number1221186-53-3
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Formula Weight372.46
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Molecular FormulaC17H16N4O2S2
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (134.24 mM)
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SMILESCn1c2cc(sc2c2cnn(Cc3cccc(N)c3)c(=O)c12)S(C)=O
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Chemical Name6-(3-aminobenzyl)-4-methyl-2-(methylsulfinyl)-46-dihydro-5H-thieno[2'3':45]pyrrolo[23-d]pyridazin-5-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Walsh M J Brimacombe K R Anastasiou D et al. ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model[M]// Probe Reports from the NIH Molecular Libraries Program. PubMed 2009.
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