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ML213

CAS No. 489402-47-3

ML213 ( ML213; ML 213; ML-213; CID-3111211 )

Catalog No. M17522 CAS No. 489402-47-3

ML213 is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

Purity : 98%

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

ML213
Note

Research use only, not for human use.
Brief Description

ML213 is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
Description

ML213, also known as CID-3111211, is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). ML213 displays > 80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay.
Synonyms

ML213; ML 213; ML-213; CID-3111211
Pathway

Others
Target

Other Targets
Recptor

Kv7.2 (KCNQ2) channels; Kv7.4 (KCNQ4) channels
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

489402-47-3
Formula Weight

257.38
Molecular Formula

C17H23NO
Purity

98%
Solubility

DMSO : 30 mg/mL 116.56 mM;
SMILES

C12C(CC(CC1)C2)C(=O)Nc1c(cc(cc1C)C)C
Chemical Name

N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-6-carboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yu, H.,et al. ACS Chem.Neurosci. 2(10), 572-577 (2011).

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