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ML204

CAS No. 5465-86-1

ML204( —— )

Catalog No. M18778 CAS No. 5465-86-1

ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 39 In Stock
10MG 61 In Stock
25MG 102 In Stock
50MG 133 In Stock
100MG 208 In Stock
200MG 268 In Stock
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Biological Information

  • Product Name
    ML204
  • Note
    Research use only, not for human use.
  • Brief Description
    ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
  • Description
    ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Nonfasted male C57BL/6 (2-3 months)Dosage:1?mg/kg Administration:Subcutaneous injection, twice a day, for 5 days (prior to LPS injection)Result:Induced mortality associated with increased hypothermia in mice with LPS-induced systemic inflammatory response.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRPC4| TRPC5
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    5465-86-1
  • Formula Weight
    226.32
  • Molecular Formula
    C15H18N2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 37 mg/mL; 163.49 mM
  • SMILES
    c12c(cccc1)c(cc(n2)N1CCCCC1)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miller M, et al. J Biol Chem. 2011 Sep 23;286(38):33436-46.
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