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ML188
CAS No. 1417700-13-0
ML188 ( —— )
Catalog No. M21931 CAS No. 1417700-13-0
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 97 | Get Quote |
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| 5MG | 160 | Get Quote |
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| 10MG | 260 | Get Quote |
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| 25MG | 533 | Get Quote |
|
| 50MG | 860 | Get Quote |
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| 100MG | 1152 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameML188
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NoteResearch use only, not for human use.
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Brief DescriptionML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
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DescriptionML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.Probe 16-(R) (ML188) is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorSARS-CoV
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Research Area——
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Indication——
Chemical Information
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CAS Number1417700-13-0
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Formula Weight433.54
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Molecular FormulaC26H31N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)NC(=O)[C@H](N(C(=O)c1ccco1)c1ccc(cc1)C(C)(C)C)c1cccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jacobs J , Grum-Tokars V , Zhou Y , et al. Discovery, Synthesis, And Structure-Based Optimization of a Series of?N?-(?tert?-Butyl)-2-(?N?-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease[J]. Journal of Medicinal Chemistry, 2013, 56(2):534-546.
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