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ML132
CAS No. 1230628-71-3
ML132( NCGC-00183434 | CID-4462093 )
Catalog No. M10910 CAS No. 1230628-71-3
ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 401 | Get Quote |
|
| 50MG | 1674 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameML132
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NoteResearch use only, not for human use.
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Brief DescriptionML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM.
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DescriptionML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.
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In Vitro——
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In Vivo——
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SynonymsNCGC-00183434 | CID-4462093
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PathwayApoptosis
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TargetCaspase
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RecptorCaspase
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1230628-71-3
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Formula Weight477.941
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Molecular FormulaC22H28ClN5O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (523.08 mM)
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SMILESO=C(O)C[C@H](NC([C@H]1N(C([C@@H](NC(C2=CC=C(N)C(Cl)=C2)=O)C(C)(C)C)=O)CCC1)=O)C#N
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Chemical Name(S)-3-((S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-cyanopropanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Boxer MB, et al. A small molecule inhibitor of Caspase 1. Probe Reports from the NIH Molecular Libraries Program [Internet].
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