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ML 154
CAS No. 1345964-89-7
ML 154( NCGC84 )
Catalog No. M27660 CAS No. 1345964-89-7
ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | Get Quote |
|
| 10MG | 317 | Get Quote |
|
| 25MG | 536 | Get Quote |
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| 50MG | 763 | Get Quote |
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| 100MG | 1053 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameML 154
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NoteResearch use only, not for human use.
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Brief DescriptionML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
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DescriptionML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
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In VitroWestern Blot Analysis Cell Line:CHO cells expressing NPSR Concentration:0.001 μM, 0.01 μM, 0.1 μM, 1 μM Incubation Time:30 min Result:Exhibited the most potent inhibition on NPS-induced ERK phosphorylation.
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In VivoAnimal Model:Male Wistar rats (300-350 g) injected with alcohol Dosage:1 mg/kg (10% Solutol, 10% N,N-dimethylacetamide, and 80% 10 mM PBS, pH 7.4) Administration:Intraperitoneal injection; once Result:Inhibited alcohol-induced central ERK phosphorylation in vivo.
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SynonymsNCGC84
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PathwayGPCR/G Protein
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TargetNeuropeptide Y Receptor
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RecptorG2019S LRRK2
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Research Area——
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Indication——
Chemical Information
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CAS Number1345964-89-7
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Formula Weight545.48
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Molecular FormulaC29H26BrN2PS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (114.58 mM)
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SMILES[Br-].Cc1c([n+]2ccccc2n1C\C=C\c1ccccc1)P(=S)(c1ccccc1)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Galanin Receptor Lig...
The chimeric peptide M35 [galanin (1-13)-bradykinin(2-9) amide] is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. The radiolabelled M35 and performed equilibrium binding studies with [125I] M35 on the rat pancreatic beta-cell line Rin m 5F.
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Galanin (1-29) (rat,...
Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
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M 1145
Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.
