Cart
sales@molnova.com
MKC8866
CAS No. 1338934-59-0
MKC8866 ( —— )
Catalog No. M23496 CAS No. 1338934-59-0
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | In Stock |
|
| 10MG | 288 | In Stock |
|
| 25MG | 484 | In Stock |
|
| 50MG | 701 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 500MG | 1962 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMKC8866
-
NoteResearch use only, not for human use.
-
Brief DescriptionMKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
-
DescriptionMKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorIRE1 RNase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1338934-59-0
-
Formula Weight361.4
-
Molecular FormulaC18H19NO7
-
Purity>98% (HPLC)
-
SolubilityDMSO:16.67 mg/mL (46.13 mM; Need ultrasonic)
-
SMILESO=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Sheng X, et al. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nat Commun. 2019 Jan 24;10(1):323.
molnova catalog
related products
-
16 alpha-Hydroxytram...
16 alpha-Hydroxytrametenolic acid can inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema.
-
Homatropine
The herbs of Atropa belladonna L.
-
Nortracheloside
Nortracheloside is a natural product of Trachelospermum, Apocynaceae.Nortracheloside can be used as a reference standard.
