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MKC8866
CAS No. 1338934-59-0
MKC8866 ( —— )
Catalog No. M23496 CAS No. 1338934-59-0
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | In Stock |
|
| 10MG | 288 | In Stock |
|
| 25MG | 484 | In Stock |
|
| 50MG | 701 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 500MG | 1962 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMKC8866
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NoteResearch use only, not for human use.
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Brief DescriptionMKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro).
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DescriptionMKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29?μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorIRE1 RNase
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Research Area——
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Indication——
Chemical Information
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CAS Number1338934-59-0
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Formula Weight361.4
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Molecular FormulaC18H19NO7
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Purity>98% (HPLC)
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SolubilityDMSO:16.67 mg/mL (46.13 mM; Need ultrasonic)
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SMILESO=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sheng X, et al. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nat Commun. 2019 Jan 24;10(1):323.
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