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MK2-IN-3

CAS No. 724711-21-1

MK2-IN-3( MK2 Inhibitor III )

Catalog No. M24735 CAS No. 724711-21-1

MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 113 In Stock
10MG 186 In Stock
25MG 404 In Stock
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Biological Information

  • Product Name
    MK2-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
  • Description
    MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MK2 Inhibitor III
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    724711-21-1
  • Formula Weight
    340.38
  • Molecular Formula
    C21H16N4O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gurgis F , kerfeldt, MC, Heng B , et al. Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2[J]. Cell Death Discovery, 2015, 1:15028.
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