MK2-IN-3( MK2 Inhibitor III )

Catalog No. M24735 CAS No. 724711-21-1

MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MK2-IN-3
Note

Research use only, not for human use.
Brief Description

MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
Description

MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis.
In Vitro

——
In Vivo

——
Synonyms

MK2 Inhibitor III
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

MAPK
Research Area

——
Indication

——

Chemical Information

CAS Number

724711-21-1
Formula Weight

340.38
Molecular Formula

C21H16N4O
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Gurgis F , kerfeldt, MC, Heng B , et al. Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2[J]. Cell Death Discovery, 2015, 1:15028.

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