MK-886

CAS No. 118414-82-7

MK-886 ( L 663536 )

Catalog No. M17858 CAS No. 118414-82-7

MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 36 In Stock
5MG 58 In Stock
10MG 102 In Stock
25MG 205 In Stock
50MG 335 In Stock
100MG 537 In Stock
500MG 1134 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MK-886
  • Note
    Research use only, not for human use.
  • Brief Description
    MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
  • Description
    MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
  • Synonyms
    L 663536
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    COX-1; COX-2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    118414-82-7
  • Formula Weight
    472.08
  • Molecular Formula
    C27H34ClNO2S
  • Purity
    98%
  • Solubility
    DMSO : ≥ 32 mg/mL 67.79 mM; H2O : < 0.1 mg/mL
  • SMILES
    CC(C)c1cc2c(cc1)n(c(c2SC(C)(C)C)CC(C)(C)C(=O)O)Cc1ccc(cc1)Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Koeberle A, et al. Eur J Pharmacol. 2009, 608(1-3):84-90.
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