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Home - Products - GPCR/G Protein - 5-HT Receptor - MIN-117

MIN-117

CAS No. 310392-93-9

MIN-117( WF-516 | WF 516 | MIN 117 )

Catalog No. M13993 CAS No. 310392-93-9

A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    MIN-117
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.
  • Description
    A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.Depression Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    WF-516 | WF 516 | MIN 117
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Depression

Chemical Information

  • CAS Number
    310392-93-9
  • Formula Weight
    538.85
  • Molecular Formula
    C25H26Cl3N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=NN=C(O1)C2=CC3=C(O2)C=CC=C3OCC(CN4CCC(CC4)C5=CC(=C(C=C5)Cl)Cl)O.Cl
  • Chemical Name
    (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. El Mansari M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jan;376(5):351-61. 2. Saijo T, et al. PLoS One. 2012;7(8):e42589. doi: 10.1371/journal.pone.0042589.
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