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MGH-CP1

CAS No. 896657-58-2

MGH-CP1 ( —— )

Catalog No. M24919 CAS No. 896657-58-2

MGH-CP1 is a potent and selective inhibitor TEAD palmitoylation. It exhibits dose-dependent and potent inhibition of TEAD2/4 auto-palmitoylation in vitro with IC50 of 710 nM and 672 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 31 In Stock
5MG 50 In Stock
10MG 80 In Stock
25MG 177 In Stock
50MG 312 In Stock
100MG 507 In Stock
500MG 1062 In Stock
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Biological Information

  • Product Name
    MGH-CP1
  • Note
    Research use only, not for human use.
  • Brief Description
    MGH-CP1 is a potent and selective inhibitor TEAD palmitoylation. It exhibits dose-dependent and potent inhibition of TEAD2/4 auto-palmitoylation in vitro with IC50 of 710 nM and 672 nM, respectively.
  • Description
    MGH-CP1 is a potent and selective inhibitor TEAD palmitoylation. It exhibits dose-dependent and potent inhibition of TEAD2/4 auto-palmitoylation in vitro with IC50 of 710 nM and 672 nM, respectively.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TEAD;TEAD2;TEAD4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    896657-58-2
  • Formula Weight
    368.5
  • Molecular Formula
    C20H24N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:74 mg/mL (200.81 mM);Ethanol:74 mg/mL (200.81 mM)
  • SMILES
    C1C2CC3CC1CC(C2)(C3)C4=CC=C(C=C4)NC(=O)CSC5=NC=NN5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li Q , Sun Y , Jarugumilli G K , et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription[J]. Cell stem cell, 2020.
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