MF-438 ( —— )

Catalog No. M22502 CAS No. 921605-87-0

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	132	In Stock
5MG	203	In Stock
10MG	311	In Stock
25MG	527	In Stock
50MG	754	In Stock
100MG	1044	In Stock
500MG	2088	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

MF-438
Note

Research use only, not for human use.
Brief Description

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
Description

MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1). In a mouse model, MF-438 shows an ED50 between 1 and 3 mg/kg.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

SCD
Research Area

——
Indication

——

Chemical Information

CAS Number

921605-87-0
Formula Weight

421.44
Molecular Formula

C19H18F3N5OS
Purity

>98% (HPLC)
Solubility

DMSO:62.5 mg/mL (148.30 mM; Need ultrasonic)
SMILES

Cc1nnc(s1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

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