MDH1-IN-1

CAS No. 2143463-31-2

MDH1-IN-1( —— )

Catalog No. M35534 CAS No. 2143463-31-2

MDH1-IN-1 (5i) is a potent MDH1 inhibitor with an IC50 of 6.79 μM for MDH1 and >40 μM for MDH2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MDH1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    MDH1-IN-1 (5i) is a potent MDH1 inhibitor with an IC50 of 6.79 μM for MDH1 and >40 μM for MDH2.
  • Description
    MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2143463-31-2
  • Formula Weight
    355.43
  • Molecular Formula
    C21H25NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (281.35 mM; Ultrasonic )
  • SMILES
    CCCCCc1ccc(OCC(=O)Nc2cccc(c2)C(=O)OC)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646.?
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