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MC3482 B
CAS No. 2922280-86-0
MC3482 B( —— )
Catalog No. M33011 CAS No. 2922280-86-0
MC3482 is a specific inhibitor of sirtuin5 (SIRT5).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | Get Quote |
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| 5MG | 107 | Get Quote |
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| 10MG | 180 | Get Quote |
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| 25MG | 273 | Get Quote |
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| 50MG | 431 | Get Quote |
|
| 100MG | 686 | Get Quote |
|
| 500MG | 1377 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMC3482 B
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NoteResearch use only, not for human use.
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Brief DescriptionMC3482 is a specific inhibitor of sirtuin5 (SIRT5).
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DescriptionMC3482 is a specific sirtuin5 (SIRT5) inhibitor.
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In VitroMC3482 inhibits sirtuin5. 50 μM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-overexpressing cells.
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research Area——
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Indication——
Chemical Information
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CAS Number2922280-86-0
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Formula Weight618.68
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Molecular FormulaC33H38N4O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 130 mg/mL (210.12 mM)
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SMILES[C@H](C(NC1=CC=CC=C1)=O)(NC(OCC2=CC=CC=C2)=O)CCCCNC(CC[C@H](NC(OCC3=CC=CC=C3)=O)C(O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Polletta L, et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy. 2015;11(2):253-70.?
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