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MC-Val-Cit-PAB

CAS No. 159857-80-4

MC-Val-Cit-PAB( —— )

Catalog No. M19787 CAS No. 159857-80-4

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MC-Val-Cit-PAB
  • Note
    Research use only, not for human use.
  • Brief Description
    MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
  • Description
    MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    159857-80-4
  • Formula Weight
    572.65
  • Molecular Formula
    C28H40N6O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:≥ 22 mg/mL (38.42 mM)
  • SMILES
    CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
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