MC-Val-Cit-PAB ( —— )

Catalog No. M19787 CAS No. 159857-80-4

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Product Name

MC-Val-Cit-PAB
Note

Research use only not for human use.
Brief Description

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
Description

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

CAS Number

159857-80-4
Formula Weight

572.65
Molecular Formula

C28H40N6O7
Purity

>98% (HPLC)
Solubility

DMSO:≥ 22 mg/mL (38.42 mM)
SMILES

CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
Chemical Name

——

1.Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders

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