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MBCQ

CAS No. 150450-53-6

MBCQ ( —— )

Catalog No. M22973 CAS No. 150450-53-6

MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MBCQ
  • Note
    Research use only, not for human use.
  • Brief Description
    MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
  • Description
    MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    150450-53-6
  • Formula Weight
    313.74
  • Molecular Formula
    C16H12ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC1=CC2=C(N=CN=C2NCC3=CC=C(OCO4)C4=C3)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Macpherson J D , Gillespie T D , Dunkerley H A , et al. Inhibition of Phosphodiesterase 5 Selectively Reverses Nitrate Tolerance in the Venous Circulation[J]. Journal of Pharmacology & Experimental Therapeutics, 2006, 317(1):188.
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