MAO-B-IN-9
CAS No. 2416910-88-6
MAO-B-IN-9( —— )
Catalog No. M35454 CAS No. 2416910-88-6
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | Get Quote |
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| 5MG | 117 | Get Quote |
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| 10MG | 187 | Get Quote |
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| 25MG | 380 | Get Quote |
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| 50MG | 542 | Get Quote |
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| 100MG | 770 | Get Quote |
|
| 500MG | 1512 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMAO-B-IN-9
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NoteResearch use only, not for human use.
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Brief DescriptionMAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
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DescriptionMAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptorBeta Amyloid | Monoamine Oxidase | Serotonin Transporter
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Research Area——
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Indication——
Chemical Information
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CAS Number2416910-88-6
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Formula Weight300.4
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Molecular FormulaC18H24N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C(NC1=CC=C(C(C)C)C=C1)=O)C2CCN(CC#C)CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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β-Amyloid 13-27
β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta amyloid formation.
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TABERSONINE HYDROCHL...
TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana is a potent inhibitor against Aβ(1?42) aggregation and toxicity.
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AC 253
Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. Blocks electrophysiological effects of Aβ in vitro. Cyclic AC 253 also available.
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