MAO-B-IN-9

Research use only, not for human use.

MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.

MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

——

——

——

Membrane Transporter/Ion Channel

Beta Amyloid

Beta Amyloid | Monoamine Oxidase | Serotonin Transporter

——

——

2416910-88-6

300.4

C18H24N2O2

>98% (HPLC)

——

O(C(NC1=CC=C(C(C)C)C=C1)=O)C2CCN(CC#C)CC2

——

(-20℃)

With Ice Pack

≥ 2 years