Sivifene can be used for research on the treatment of cutaneous metastases from cancer.

5-hydroxytryptamine is a natural product from animals.

Neuropeptide W-30 (human) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (human) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. Neuropeptide W-30 (human)activates and binds to both GPR7 and GPR8 at similar effective doses.