Cortistatin-14 is a neuropeptide have structural similarity to somatostatin-14. It is produced in the cortex and hippocampus of central nervous system.

MFZ 10-7 is anegative allosteric modulator of the mGluR5. In rats, MFZ 10-7 (i.p.) inhibits cocaine-induced reinstatement of drug-seeking behavior, cocaine-associated cue-induced cocaine-seeking behavior and intravenous cocaine self-administration.

SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM). SB 290157 is a competitive antagonist of 125I-C3a radioligand binding to rat basophilic leukemia-2H3 cells expressing the human C3aR (RBL-C3aR, IC50 of 200 nM).