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Bovine Pineal Antireproductive Peptide

CAS No. 71730-64-8

Bovine Pineal Antireproductive Peptide( ——— )

Catalog No. M42057 CAS No. 71730-64-8

Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bovine Pineal Antireproductive Peptide
  • Note
    Research use only, not for human use.
  • Brief Description
    Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5.
  • Description
    Threonyl-seryl-lysine has antigonadotropic activity isolated from bovine pineals.
  • In Vitro
    ———
  • In Vivo
    Threonyl-seryl-lysine (175 ng, i.p.) reduces the 5-day compensatory ovarian hypertrophy in unilaterally ovariectomized (UO) mice.Threonyl-seryl-lysine (1 or 5 μg, i.p.) delays vaginal opening time in female Charles River CD rats.Threonyl-seryl-lysine (1 and 10 μg, s.c., for 15 days) increases the weight of ovaries and of adrenals in mice.Animal Model:Unilaterally ovariectomized (UO) mice Dosage:175 ng Administration:Intraperitoneal injection (i.p.)Result:Reduced serum follicle stimulating hormone (FSH) in UO mice.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    71730-64-8
  • Formula Weight
    334.38
  • Molecular Formula
    C13H26N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Orts RJ, et al. Inhibitory properties of a bovine pineal tripeptide, threonylseryllysine, on serum follicle-stimulating hormone. Neuroendocrinology. 1980 Aug;31(2):92-5. ?
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