Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR.

ML382 is a potent and selective MrgX1 positive allosteric modulator(EC50 : 190 nM).ML382 enhances the ability of BAM8-22 to inhibit high-voltage-activated Ca2+ channels and attenuate spinal nociceptive transmission, both BAM8-22 and ML382 effectively attenuated evoked, persistent, and spontaneous pain without causing obvious side effects.?

Guanosine monophosphate also known as guanylic acid or 5'-GMP belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase.